2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Phosphodiesterase (PDE)
  5. Phosphodiesterase (PDE) Isoform
  6. Phosphodiesterase (PDE) Modulator

Phosphodiesterase (PDE) Modulator

Phosphodiesterase (PDE) Modulators (3):

Cat. No. Product Name Effect Purity
  • HY-N10149
    Nauclefine
    		Modulator 99.65%
    Nauclefine is an indole alkaloid isolated from Nauclea officinalis. Nauclefine acts as a PDE3A modulator to induce cancer cell apoptosis through a PDE3A-SLFN12-dependent death pathway.
  • HY-103035R
    BIO-32546 (Standard)
    		Modulator
    BIO-32546 (Standard) is the analytical standard of BIO-32546 (HY-103035). This product is intended for research and analytical applications. BIO-32546 (example 12b, S-isomer) is an autotaxin (ATX) modulator (IC50: 1 nM), extracted from the patent US20170158687A1.
  • HY-134406
    6-Cl-cPuMP sodium
    		Modulator
    6-Cl-cPuMP (sodium) is a cAMP analog with active chlorine function. 6-Cl-cPuMP (sodium) has good membrane permeability and phosphodiesterase (PDE) stability. 6-Cl-cPuMP (sodium) can be used for nervous system research.